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European Nuclear Medicine Guide
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European Nuclear Medicine Guide
Chapter 4.7

Effectiveness

There are other treatments that can be employed for synovitis:

  • Surgical (open or arthroscopic) synovectomy. This treatment is used for many forms of arthritis.

  • Intra-articular osmic acid or chemical synovectomy (hardly used anymore).

  • The indications for these other treatments are similar to those for radiosynoviorthesis, and these methods deliver similar effects.

  • However, advantages of radiosynoviorthesis over surgical synovectomy are:

  • Radiosynoviorthesis is a simple procedure which is not very demanding of the patient;

  • It requires no anaesthetic;

  • The rehabilitation time is short;

  • The duration for admission is shorter.

A disadvantage of radiosynoviorthesis is the potential leakage of the radiopharmaceutical to the lymph nodes and liver. However, this is normally below 5% of the injected activity [6].