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European Nuclear Medicine Guide
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European Nuclear Medicine Guide
Chapter 4.3

Patient Selection

Patients selection criteria are similar for all the above radiopharmaceuticals: 

Inclusion criteria

  • Feasible intra-articular injection in the meta-carpophalangeal, proximal interphalangeal, or meta-tarsophalangeal joint for Erbium -189, shoulder joint for Rhenium-186 and into the knee joint for Yttrium-89. 

  • Persistent synovitis despite adequate medication and/or intra-articular corticosteroids;

  • Pigmented Villonodular Synovitis 6-12 weeks after arthroscopic and/or open surgical synovectomy;

  • Recurrent joint haemorrhage (one joint) in patients with haemophilia.